Study Finds Aspirin May Increase Anaemia Risk In Older Adults

 

It has been front and centre in medicine cabinets for over a century but researchers are now warning seniors to think twice about aspirin. A new study has found adults over 70 who take a daily dose have a higher risk of becoming anaemic.

Daily Aspirin May Cause Anemia In Seniors

Aspirin is a medication commonly used by seniors to prevent blood clots and reduce the risk of heart attack and stroke. However, recent studies have shown that daily aspirin use may lead to the development of anemia in this population.

Anemia is a significant health problem in the elderly, characterized by a decrease in the number of red blood cells or hemoglobin levels in the blood, which can lead to fatigue, weakness, and other complications. The study followed over 18,000 adults aged 65 and older from the US and Australia and found that those who took aspirin daily had a 10% higher risk of developing anemia than those who did not.

This finding has raised concerns among healthcare professionals regarding the use of aspirin as a preventative measure in seniors. In this article, we will explore the findings of this study, the potential risks of aspirin-induced anemia, and what doctors can do to monitor and prevent this condition.

Key Takeaways

  • Aspirin usage has been common among adults to prevent blood clots but is no longer recommended for all older adults due to increased risk of major bleeding.
  • A study on aspirin and anemia followed over 18,000 adults who were 65 and older from the US and Australia and found that adults who took aspirin were 20% more likely to be anemic than those who didn’t take it.
  • Those on aspirin regimens also had slightly lower levels of hemoglobulin and ferritin, which help blood cells carry oxygen, and the difference remained even when adjusted for other factors.
  • Aspirin may cause anemia by blocking an enzyme important for the maintenance of the lining of the stomach and intestines, which can cause small amounts of blood to leak out over time. People who have other risks for anemia, such as inflammatory diseases or chronic renal insufficiency, should consider monitoring hemoglobin levels if they are taking aspirin.

Aspirin and Blood Clots

Aspirin is commonly used to prevent blood clots, especially among older adults who are at an increased risk for heart attack and stroke. However, a recent study suggests that daily aspirin use may also lead to anemia in seniors. Anemia is a health condition characterized by a lack of red blood cells or hemoglobin, which can result in fatigue, weakness, and shortness of breath.

The study followed over 18,000 seniors from the US and Australia who were 65 years or older for five years. Half of the participants took 100 milligrams of aspirin daily, while the other half took a placebo.

The results showed that seniors who took aspirin were 20% more likely to develop anemia than those who didn’t take it. This suggests that doctors should consider monitoring hemoglobin levels in seniors who are taking aspirin, especially those with other risk factors for anemia.

Study on Anemia Risk

The study aimed to investigate the potential factors contributing to the prevalence of anemia in the elderly population, particularly focusing on the role of daily aspirin usage. Anemia is a significant problem in the elderly, and it is often linked to poor health outcomes.

The study followed over 18,000 adults who were 65 and older from the US and Australia, with half taking 100 milligrams of aspirin a day and the other half taking a placebo. The results showed that the adults who took aspirin were 20% more likely to be anemic than those who didn’t take it, with 24% of seniors in the daily aspirin group developing anemia within five years compared to 20% of those in the placebo group.

Moreover, the study found that those on aspirin regimens had slightly lower levels of hemoglobulin and ferritin, which help blood cells carry oxygen. The difference remained even when adjusted for other factors, indicating that aspirin usage could be a contributing factor to anemia in the elderly.

Aspirin makes it harder for blood to clot by blocking an enzyme important for the maintenance of the lining of the stomach and intestines. This can cause small amounts of blood to leak out over time, eventually causing anemia.

Therefore, doctors should consider monitoring hemoglobin levels if patients have multiple risk factors, including aspirin use, and take necessary measures to prevent anemia in the elderly population.

Aspirin and Anemia Mechanism

One mechanism that contributes to anemia in elderly patients is the inhibition of an important enzyme that plays a role in the maintenance of the lining of the stomach and intestines.

Aspirin, a commonly used medication among older adults to prevent blood clots, blocks this enzyme, leading to small amounts of blood leaking out over time.

This chronic blood loss eventually causes anemia, a condition in which the body does not have enough healthy red blood cells to carry oxygen to the tissues.

The inhibition of this enzyme is particularly problematic for elderly patients who already have other risk factors for anemia, such as inflammatory diseases or chronic renal insufficiency.

Therefore, doctors should consider monitoring hemoglobin levels in patients who are taking aspirin and have multiple risk factors for anemia.

By doing so, they can detect anemia early and provide appropriate treatment to prevent further complications.

Conclusion

In conclusion, the use of aspirin to prevent blood clots and reduce the risk of heart attack and stroke is a common practice among older adults. However, recent studies have shown that daily aspirin use may lead to the development of anemia in seniors.

Anemia is a significant problem in the elderly and is linked to worse health outcomes. The study, which followed over 18,000 adults aged 65 and older from the US and Australia, highlights the potential risks of aspirin-induced anemia.

It is important for healthcare providers to be aware of this potential side effect and consider monitoring the hemoglobin levels of older adults who take aspirin daily. Further research is needed to determine the optimal dosage and frequency of aspirin use to balance the benefits of preventing blood clots with the risks of anemia.

Overall, healthcare providers should weigh the potential risks and benefits of aspirin use in each individual patient and consider alternative therapies if appropriate.

Sources

https://edition.cnn.com/2023/06/19/health/daily-aspirin-anemia/index.html

https://www.webmd.com/healthy-aging/news/20230620/aspirin-warning-anemia-may-increase-with-use-in-older-adults

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